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Research + Registry

Solve M.E. invests in innovative scientific studies to address knowledge gaps in ME/CFS, Long Covid and other post-infectious diseases. We fund a portfolio of research projects at some of the most prestigious medical centers and research laboratories in the United States and abroad. We partner with leading experts in the field and build new collaborations.

Our dedication to collaborative ME/CFS research is longstanding and includes initiatives such as our You + ME Registry, which gathers + provides access to patient-provided data, our Ramsay Research Grants, which assist early-career researchers, our partnership with Action for M.E., which funds postdoctoral fellowships, and our groundbreaking collaboration with UCLA, which sponsors leading-edge studies.

Solve M.E. invests in translational research — research that transforms an idea into a study, a study into diagnostics and clinical trials, and clinical trials into approval of available treatments.

Ramsay Research Grant Program

The Ramsay Research Grant Program is the largest source of private, peer-reviewed, research grants in the field of ME/CFS and one of the only avenues researchers have to obtain funding for pilot studies. The Ramsay Program has had huge success in attracting new researchers to the ME/CFS and Long Covid fields and ensuring they stay engaged, while also facilitating applications for larger grants based on promising pilot data.

Since its launch in 2016, Solve M.E. has invested over $1 million in Ramsay Grants, which in turn helped researchers receive over $8 million in additional research funding — a 8X return on the investment. 

Through Ramsay, we’ve built an extensive network of 91 scientists engaged in ME/CFS research, with a growing number of them making meaningful scientific contributions.

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The You + ME Registry and Biobank

The You + ME Registry and Biobank is an online clinical study committed to identifying a cure for myalgic encephalomyelitis (also known as chronic fatigue syndrome or ME/CFS), Long Covid and other post-infection diseases. The Registry is a fundamental strategic initiative aiming to create the world’s largest longitudinal ME/CFS database and make it available to researchers around the world. We incorporated Long Covid — which shares many similarities with ME/CFS — so that understanding one can illuminate the other.

Designed for and by patients, the Registry community is made up of people with ME/CFS, people with Long Covid and control volunteers collectively providing the research community with critical insight into the lived experience and genetics of these and other post-viral illnesses. 

We’re confident that the energy of big data will unleash otherwise elusive insights about ME/CFS and Long Covid as it has for other complex conditions, such as cancer. Cohort selection within the Registry can expedite a study’s recruitment and maximize its success. With thousands already enrolled, the Registry is growing rapidly, becoming a richer resource for researchers every day.

The Registry strategically strengthens and expands our commitment to research, powering the possibility of experiments designed to drive directly to a cure.

Interested in conducting research or contacting our team?

Discover More

How the Study of COVID-19 Will Impact Our Understanding of ME/CFS

How the You + ME Registry Works

You + ME: A Registry for the Whole ME/CFS Community

Help Us Stop The Long Haul

Solve M.E. relies on the generous support of donors like you to continue making strides in ME/CFS, Long Covid, and post-viral disease research. Your support could lead to the next big research breakthrough.

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