The Solve ME/CFS Initiative (Solve M.E.) was the first private funder of ME/CFS research in the U.S., investing in innovative scientific studies to address knowledge gaps in ME/CFS, Long Covid, and other associated conditions. We fund a portfolio of research projects at some of the most prestigious medical centers and research laboratories in the United States and abroad. We partner with leading experts in the field and build new collaborations.
Our dedication to collaborative ME/CFS research is longstanding and includes initiatives such as our Ramsay Research Grants, which assist early-career researchers, the Solve ME/CFS Catalyst Awards, delivering rapid-response funding to ensure high-impact studies reach completion, publication, or the next phase faster, and the real-world data platform Solve Together, which gathers and provides access to patient-provided data.
Solve M.E. invests in translational research — research that transforms an idea into a study, a study into diagnostics and clinical trials, and clinical trials into approval of available treatments.
By funding both nearly complete studies from established researchers and bold pilot projects from rising scientists, we accelerate progress on two fronts—delivering near-term results while also seeding the next generation of breakthroughs. It’s a powerful, complementary strategy that gives us the best chance to find effective treatments and, ultimately, a cure.
Launched in 2025, the Catalyst Awards are a focused initiative to ensure that promising research doesn’t lose momentum—especially in the face of unpredictable federal funding cycles. These awards provide strategic support to help studies reach key milestones such as publication, translation to clinical application, or advancement to the next phase of investigation.
Solve’s Ramsay Research Grant Program is the largest source of private, peer-reviewed, research grants in the field of ME/CFS and one of the only avenues researchers have to obtain funding for pilot studies. The Ramsay Program has had huge success in attracting new researchers to the ME/CFS and Long Covid fields and ensuring they stay engaged, while also facilitating applications for larger grants based on promising pilot data.
Since its launch in 2016, Solve M.E. has invested over $1.4 million in Ramsay Grants, which in turn helped researchers receive over $48 million in additional research funding — a 34X return on the investment.
Through Ramsay, we’ve built an extensive network of nearly 100 scientists engaged in ME/CFS and Long Covid research, with a growing number of them making meaningful scientific contributions.
Solve Together is a platform designed to collect clinical data about post-infectious diseases. This data is made available to researchers and will be used to identify participants eligible for clinical studies. The platform also empowers patients to make reports for their doctors, connect a health tracking wearable device, and identify their unique symptom and health patterns.
Solve M.E. relies on the generous support of donors like you to continue making strides in ME/CFS, Long Covid, and post-viral disease research. Your support could lead to the next big research breakthrough.
350 N Glendale Ave.
Suite B #368
Glendale, CA 91206
SolveCFS@SolveCFS.org
704-364-0016
EIN: 56-1683450
