Solve Together

Solve Together is a dynamic, patient-centered platform that integrates multiple data sources designed to speed up the discovery of treatments and cures. We make data on post-infectious diseases accessible to researchers, expediting the identification of diagnostic and therapeutic targets. Patients can create reports for their doctors, sync health-tracking wearables, and discern their distinct symptom and health trends. Solve Together will also enable Solve to connect researchers with individuals interested in participating in clinical research studies.

Any U.S. adult can join Solve Together, whether they have ME/CFS, Long Covid, other post-viral fatigue-related illnesses, or none of these conditions (serving as “Control” participants). Joining is free, voluntary, and participants can opt out anytime.

For step-by-step support on getting started, consult our Quick Start Guide here.

Learn more about how Solve Together is accelerating collaborative research for ME/CFS and Long Covid here.

Improved features include:

Linking to wearables and Electronic Health Records

Downloadable reports for doctor visits

Providing data with less time and energy

Transforms your data into clinical breakthroughs!

  • Track your symptoms

  • Connect wearable devices

  • Link electronic health records

  • Download reports to share with providers

  • Set pacing notifications

  • Connect to clinical trials

Solve Together Goals:

Solve envisions a world free of ME/CFS, Long Covid and other post-infection diseases. That’s why we’ve created Solve Together, a data collection platform that serves as a catalyst for clinical researchers to access patients, controls, and contextual data in real-time for research that drives better diagnostics and therapeutics.


Support personal tracking of symptoms and experiences for individual care management.


Create a comprehensive, integrated research database with the goal of finding treatments and cures.


Help recruit for clinical studies.

Frequently Asked Questions

While Solve Together is launching to US residents only, we hope to expand internationally over time.  If you would like to be notified when Solve Together is available in your country, please join our email newsletter. 
In the meantime, if you want to track your symptoms and/or use pacing notifications, you may use the web version of Symptom Shark ( If you live in Australia, Canada, Kenya, or the UK, you may get all the features of symptom through the mobile app “MyDataHelps” available in iOS and Android.
If you reside in Canada, Austria, Germany, Norway, Ireland, the Netherlands, Poland, the United Kingdom, Mexico, or Australia, the Visible Long Covid ME/CFS app for iPhone or Android is another product designed for those with ME/CFS, Long Covid, and related conditions.

Solve Together is built on the MyDataHelps platform, which is HIPAA compliant and is used by some of the largest research institutions in the U.S., including many studies conducted by the National Institutes of Health. We are committed to the highest privacy standards for collecting and storing participant data.

Solve Together is a continuation of our You + ME Registry and your participation dates back to your You+ME registration.

Pacing notifications can only be sent when Symptom Shark receives data from Fitbit or Apple Health. Sometimes there can be delays in syncing that result in notifications not being sent in a timely fashion. Additionally, if you are using an Apple Health device (Apple Watch, Garmin, Withings, etc.) data can only sync when your phone is unlocked.

If data is not coming in, follow these steps to troubleshoot:

  • Check that your phone has bluetooth enabled
  • Check that your wearable device is syncing with it’s app (e.g. the Fitbit or Garmin app)
  • Wait a few minutes. Especially when you first sync a device, it may take a few minutes for data to come in.

If you are connecting via Apple Health, there are some additional troubleshooting steps you can take:

  • Ensure that your device is connecting to Apple Health. For instance, if you are using a Garmin or Withings device, you will need to go into the Garmin or Withings app to enable the device to send data to Apple Health.
  • Check that you have enabled the right permissions for MyDataHelps to access Apple Health data:
  • Open the “Settings” app
  • Select “Privacy”
  • Select “Health”
  • Select “MyDataHelps”
  • Enable the categories of data you would like to share with Symptom Shark
  • Ensure that the data you are looking for is showing in Apple Health and in the Symptom Shark “Activity” view. For instance, the steps you see in Apple Health for yesterday should match thet steps you see in Symptom Shark for yesterday.”

That’s absolutely fine. Upon entering Solve Together, you will be consenting to participate in the data collection. Separately, you will be offered the option of connecting your medical record and/or wearable devices. This is optional and not a required aspect of participation.

Solve Together is a platform not only for clinical study recruitment but also for collecting clinical data from you that can be used for analyses. You’ll also be able to track your symptoms at your own personal pace. We’ll collect data from your wearables (e.g. Fitbit and Apple watches) and/or your electronic health records so that you can create a report for yourself and for your doctors. You can join Solve Together and participate in other studies and platforms if you choose.

Real World Data (RWD) are data routinely collected outside of the context of a clinical trial. They may include patient reports, which can be collected over a longer period of time, as well as passive-collection sources, such as electronic medical records or wearable devices. These data offer a perspective into what happens in the “real world” outside of the specific context of a clinical trial and can help inform clinical research.  RWD collection is typically more agile and affordable to collect than clinical trial data. Moreover, clinical trials do not usually share data collected with patients. 

While clinical trial data are excellent to test new therapeutics, therapeutics are developed based on hypotheses and targets. For ME/CFS/LC/PI, there is a need to understand more about the disease and its possible subtypes in order to form hypotheses and identify potential targets. Early-stage studies are the initial steps to the development of diagnostic and therapeutic trials. Real World Data is the data we use for these studies and it is data that is outside the context of a clinical trial.

While the term “registry” can mean many things, the two main kinds according to the NIH are a contact registry and natural history registry. Solve Together is both. It is a natural history registry designed to collect uniform clinical data about post-infectious diseases. And it is a contact registry that will be used to recruit for clinical studies. The term “registry” alone is not specific enough to capture all the features of Solve Together, since it is natural history,  recruitment, and a way for patients to create reports to bring to their doctors, link a wearable, track symptoms, and observe their own health patterns.

Patients were critical to the development of the symptom tracker, were asked to test the app and provide feedback, and were a part of the initial platform development and as beta testers. The development of the new platform was also based on the generous feedback we received from patients using the You + ME Registry.

Solve envisions a platform that can serve as a catalyst for clinical researchers to access patients, controls, and contextual data in real-time for research that leads to better diagnostics and therapeutics. This platform is enhanced by integration with wearables, medical records, and other data sources for those patients who consent.

Why is patient-reported data important?

Diseases such as ME/CFS and Long Covid are poorly understood, not well- characterized, and suffer from a shortage of longitudinal information about their dynamic nature. Real World Data will improve understanding of these diseases and possible disease subtypes by informing early-stage studies, which are critical first steps in the development of diagnostic and therapeutic trials.

Participants will be able to use Solve Together to share data and reports with their healthcare providers, identify patterns in their own lived experience, as well as propose ideas for research based on these data.


Real World Data is routinely collected data outside the context of a clinical trial. These data includes patient-reported or observational data, which can be collected from passive-collection sources (e.g., a Fitbit), and  for a longer duration of time than the typical clinical trial.