Ramsay Research Grant Program
Solve M.E. supports research into the underlying causes of ME/CFS and Long Covid through the Ramsay Research Grant Program, an open, peer-reviewed competition for grants to support pilot studies and data analysis. The Ramsay Program has been successful in attracting new scientists to the field of ME/CFS, providing much-needed funding for researchers to engage with the science of the disease and build pilot data.
Since 2016, 33 studies have been supported by Ramsay Grants. There is a network of over 85 research collaborators who have been involved in the Ramsay Program. Half of the principal investigators on these projects applied their expertise to study ME/CFS for the first time and 17 of the projects involved early-career stage researchers.
Stay tuned for additional details and information about applying.
The Ramsay Grant Program has three main objectives:
Two types of Ramsay Grants:
Lab-Based Research Grants
Ranging from $35,000 to $55,000 for one year, with the possibility of renewal for projects yielding promising results.
Supports studies that analyze the data in the You + ME Registry. They have an upper limit of $10,000 for six months, with the possibility of renewal for projects yielding promising results.
In 2021, Long Covid research and the availability of a rich longitudinal data set in the You + ME Registry were available for the first time.
Applications receive a rigorous, double-blind peer review to ensure projects of the highest quality are selected. Applications receive two independent reviews and proposals are ranked numerically on a defined scale based on significance, innovation, approach, and overall impact.
Leveraging Impact: Ramsay Grant Priorities
- Fund more researchers than ever before, with a focus on collaboration
- Require Ramsay investigators to share both positive and negative results to allow other researchers to build on their findings and counteract publication bias
- Mobilize Ramsay investigators to complete a visibility or advocacy action (e.g. writing an op-ed or visiting with a lawmaker to advocate for an increase in research dollars) as part of their projects
Stupski Data Analysis Awards
In 2021, Solve expanded the Ramsay Program by launching the Stupski Awards to fund projects that analyze You + ME Registry data. These new grants honor Joyce Stupski, whose generous support of research and dedication to Solve M.E. will be sorely missed.
Recipients of the first-ever Stupski Awards are Jennifer Stone, PhD, and Efthymios Kalafatis, MSc.
Ramsay Grants have supported:
Publications resulting from Ramsay-supported research include:
“Systemic Antibody Responses Against Human Microbiota Flagellins Are Overrepresented in Chronic Fatigue Syndrome Patients” Scientific Advances
“Evidence of Widespread Metabolite Abnormalities in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Assessment with Whole-Brain Magnetic Resonance Spectroscopy” Brain Imaging and Behavior
Read more about Dr. Jarred Younger here.
“CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome,” Frontiers in Immunology
“HHV-6 Encoded Small Non-Coding RNAs Define an Intermediate and Early Stage in Viral Reactivation,” Genomic Medicine
“Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model,” Frontiers in Immunology
“Antibodies to Human Herpesviruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients,” Frontiers in Immunology
“Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome,” mmunoHorizons
Read more about Dr. Bhupesh Prusty here.
“Autoimmunity-Related Risk Variants in PTPN22 and CTLA4 Are Associated With ME/CFS With Infectious Onset,” Frontiers in Immunology