One of our core missions is to facilitate research on ME/CFS, Long Covid, and associated conditions. In fact, Solve is one of the largest private funders in the United States for peer-reviewed research focused on ME/CFS. Through Solve’s Ramsay Research Grant Program and Solve ME/CFS Catalyst Awards, our donors have funded over 40 scientists working to understand ME/CFS and Long Covid and develop new treatments for people with these diseases.
Importantly, Solve-affiliated researchers have won substantial follow-up funds from other institutions. Our researchers have received over $1.6 million from Solve and gone on to win another $68 million from other groups—a 43-fold return on investment for our donors.
Meet some of our awardees below and click on the pictures to learn more about the research projects we’re proud to fund.
“Discovery of pathological autoantibodies in ME/CFS and post-acute sequelae ofSARS-CoV-2 infection”Principal Investigator: Aaron Ring (MD, PhD)Yale…
“Probing Functional Autoantibodies in Patients with ME/CFS.”
“Blood-brain barrier imaging as a biomarker for ME/CFS”Principal Investigator: Alon Friedman (MD, PhD)Dalhousie University and Emagix,…
“Targeting Atg13 in an Animal Model for ME/CFS”Principal Investigator: Avik Roy, PhD Home Avik Roy,…
“HHV-6 Mediated Mitochondrial Modulation and Its Association to ME/CFS”PI: Bhupesh Prusty, PhDUniversity of Wuerzberg Home…
“Possible class II MHC deficiency in patients with Myalgic Encephalomyelitis or Chronic Fatigue Syndrome (ME/CFS)”Principal…
“Metabolic Changes in T Cells & Monocytes”PI: Carmen Scheibenbogen, MDCharité—Universitätsmedizin Berlin in Germany Home CARMEN…
“Autoimmune Signature in ME/CFS”PI: Carmen Scheibenbogen, MDCharité—Universitätsmedizin Berlin in Germany Home CARMEN SCHEIBENBOGEN “Autoimmune Signature…
“Enhanced External Counterpulsation (EECP), Non-invasive Approach to Treat Long Covid Fatigue”Principal Investigator: Dana Yelin, MD…
“Microbial aryl hydrocarbon receptor agonists in ME/CFS”Principal Investigator: David Esteban (PhD)Vassar College Home DAVID ESTEBAN “Microbial…
“Endogenous retroviruses (ERVs) and their expression in chronic fatigue syndrome”PI: Dawei Li, PhDUniversity of Vermont…
“Effect of Stellate Ganglion Block on ME/CFS Symptoms and Plasma Metabolites”Principal Investigator: Deborah Duricka, PhDCo-Investigator:…
“Application of machine learning and text analytics in a cohort of people with ME/CFS and…
“Whole genome sequencing and analysis of ME/CFS”PI: Elizabeth Worthey, PhDHudsonAlpha Institute Home LIZ WORTHEY AND…
“Gut Microbiome & Autoantigens”PI: Eran Segal, PhDWeizmann Institute of Science Home ERAN SEGAL “Gut Microbiome…
“Investigating alterations in the intestinal virome in CFS/ME”PI: Fiona NewberryQuadram Institute and the University of…
“Unraveling Endothelial Function in ME/CFS” Principal Investigator: Francisco Westermeier (PhD)FH JOANNEUM University of Applied Sciences,…
“Metabolic Analysis Of B-cell Maturation In ME/CFS”PI: Geraldine (Jo) Cambridge, PhDUniversity College London (UCL) Home…
“Physiological and cognitive function in patients with PASC or ME before and afterinspiratory muscle training”Principal…
“Cross-sectional study to assess the prevalence of APOE e4 alleles in patients with ME/CFS and…
“Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance…
“ME/CFS and Long Covid: Are they the same condition?” Principal Investigator: Jennifer Stone (PhD) Australian National…
“Biomarkers of mitochondrial dysfunction and signaling in ME/CFS”PI: Jonas Blomberg, MD, PhD, Anders Rosén, MD,…
“Biomarkers for initiation (infection) and metabolic derangement in ME/CFS”PI: Jonas Blomberg, MD, PhD, Jonas Bergquist,…
“Immunosenescence, Premature Aging of the Immune System in ME/CFS and the Response to Fecal Microbe…
“PARsing Post-Exertional Malaise: Does Post-Exertional Autonomic Recovery (PAR) Impact Post-Exertional Malaise? ”PrincipaI Investigator: Kegan Moneghetti,…
“Enriching the You + ME Registry: Exploring Access-to-care and Other Real World Data”Principal Investigator: Kevin…
“Extensive characterization of the ME/CFS blood and cerebrospinal fluid microbiome + virome” Principal Investigators: Nikos…
“Altered T cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”Principal Investigators: Liisa Selin (PhD), Anna Gil…
“Epigenetics in Immune Cells”PI: Lubov Nathanson, PhDNova Southeastern University Home LUBOV NATHANSON “Epigenetics in Immune…
“ME/CFS In a Petri Dish”PI: Assistant Professor Malav Trivedi, PhDNova Southeastern University Home MALAV TRIVEDI…
“Brain perfusion changes in chronic fatigue syndrome before and after exercise challenge”Principal Investigators: Michael Van…
“Micro-clots, Skeletal Muscle Pain and Post-Exertional Malaise in Patients with Long Covid: From Pathophysiology to…
“Symptoms, mechanisms and sex: Exploring the sex differences in ME/CFSthrough integrated computational analyses”Principal Investigator: Sara Ballouz…
“Defining the Postural Contributors to Post-Exertional Malaise (PEM) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”Principal Investigator:…
“Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions.”
“Extracellular vesicles from ME/CFS Patients and their effect on human mast cells and microglia mediators…
“Characterization of Janus kinase (JAK) activation profiles in ME/CFS subgroups”PI: Vincent Lombardi, PhDUniversity of Nevada,…
