Deciphering PEM is a critically important area of research for ME/CFS. Despite the lack of gravity and specificity a term like “post exertional malaise” signifies, research into what it is and how to measure it is some of the most important research – and most popular. The Journal of Translational Medicine ranked two articles dealing with ME/CFS among its most highly accessed for 2014. LEARN MORE…
Research Digest – September 2014: Cortisol in ME/CFS
Cortisol is an essential hormone for immune function and many studies have shown that cortisol is low in ME/CFS patients – known as hypocortisolism. In this month’s research digest, we review three studies that look at the effect of cortisol on function and post-exertional malaise in ME/CFS…
Research Digest – May 2014: Post-Exertional Malaise
Post-exertional malaise (PEM) is characteristic of ME/CFS – considered a hallmark of the disease. Despite this hallmark status, research has not defined what PEM is or how to measure it. Patients describe PEM as a crash that occurs following physical or mental exertion. In his comments to the IOM and in our May Guest […]