Meet the Researchers

2021

The Solve M.E. Ramsay Grant Program is designed to build a research workforce for ME/CFS and to allow researchers to generate data to support larger grant applications.

Currently in its sixth year, the Ramsay network now includes more than 80 researchers around the world and has resulted in more than $7 million dollars of additional research funding for ME/CFS.

We’re now accepting applications for 2022! Learn more and apply here

Meet the teams below and click on the pictures to learn more about their research projects.

Sara Ballouz, PhD

“Symptoms, mechanisms and sex: Exploring the sex differences in ME/CFSthrough integrated computational analyses”Principal Investigator: Sara Ballouz…

Heather Edgell, PhD

“Physiological and cognitive function in patients with PASC or ME before and afterinspiratory muscle training”Principal…

David Esteban, PhD

“Microbial aryl hydrocarbon receptor agonists in ME/CFS”Principal Investigator: David Esteban (PhD)Vassar College Home DAVID ESTEBAN “Microbial…

Alon Friedman, MD, PhD

“Blood-brain barrier imaging as a biomarker for ME/CFS”Principal Investigator: Alon Friedman (MD, PhD)Dalhousie University and Emagix,…

Aaron Ring, MD, PhD

“Discovery of pathological autoantibodies in ME/CFS and post-acute sequelae ofSARS-CoV-2 infection”Principal Investigator: Aaron Ring (MD, PhD)Yale…

This year, Solve expanded the Ramsay Program by launching the Stupski Awards to fund projects that analyze You + ME Registry data. These new grants honor Joyce Stupski, whose generous support of research and dedication to Solve M.E. will be sorely missed.

Recipients of the first-ever Stupski Awards are Jennifer Stone, PhD, and Efthymios Kalafatis, MSc.  Click on the pictures below to learn more about their research projects.

Jennifer Stone, PhD

“ME/CFS and Long Covid: Are they the same condition?”Principal Investigator: Jennifer Stone (PhD)Australian National University Home…

Efthymios Kalafatis

“Application of machine learning and text analytics in a cohort of people withME/CFS and people…

Let the Ramsay Researchers know what their work means to you!

Use this form to send them a note with congrats and your hopes for their scientific studies that will unfold over the coming years.

2019

2019 was our biggest year yet! We had over 30 researchers working across seven projects. The group represented 12 academic centers and organizations. Three of the studies were done collaboratively, integrating scientists from different labs.

Meet the teams below and learn more about their research projects.

Liisa Selin and Anna Gil

“Altered T cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”Principal Investigators: Liisa Selin (PhD), Anna Gil…

Bruno Paiva, PhD

“Possible class II MHC deficiency in patients with Myalgic Encephalomyelitis or Chronic Fatigue Syndrome (ME/CFS)”Principal…

Shad Roundy, PhD

“Defining the Postural Contributors to Post-Exertional Malaise (PEM) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)”Principal Investigator:…

Kris Fobes, Nikos Kyripides, PhD, David Paez-Espino, PhD

“Extensive characterization of the ME/CFS blood and cerebrospinal fluid microbiome + virome” Principal Investigators: Nikos…

Francisco Westermeier, PhD

“Unraveling Endothelial Function in ME/CFS” Principal Investigator: Francisco Westermeier (PhD)FH JOANNEUM University of Applied Sciences,…

Kegan Moneghetti, PhD, MMS (hons), FRACP

“PARsing Post-Exertional Malaise: Does Post-Exertional Autonomic Recovery (PAR) Impact Post-Exertional Malaise? ”PrincipaI Investigator: Kegan Moneghetti,…

Michael Van Elzakker, PhD and Kenneth Kwong, PhD

“Brain perfusion changes in chronic fatigue syndrome before and after exercise challenge”Principal Investigators: Michael Van…

2018

The 2018 Request for Applications (RFA) received an enthusiastic response; double the number of applications were submitted compared to the 2017 cycle. From a collection of high quality proposals, seven projects received Ramsay funding at the beginning of 2019. Broadly, the investigators are researching mitochondrial dysfunction, immune-mediated inflammation, cell signaling, genetics, and infectious triggers. 

The Ramsay 2018 PI’s include two expert researchers leading their first original studies in ME/CFS and two highly innovative early-career stage researchers. This group of researchers has a particular emphasis on unbiased bioinformatics approaches and the use of methods novel to the ME/CFS field, such as evaluating exosomes (vesicles released from cells that play a role in intercellular communication) and producing reprogrammed neurons to examine neuro-metabolic and molecular changes. 

Vincent Lombardi, PhD

“Characterization of Janus kinase (JAK) activation profiles in ME/CFS subgroups”PI: Vincent Lombardi, PhDUniversity of Nevada,…

Theoharis Theoharides, MD, PhD

“Extracellular vesicles from ME/CFS Patients and their effect on human mast cells and    microglia mediators…

Elizabeth Worthey, PhD and Camille Birch, PhD

“Whole genome sequencing and analysis of ME/CFS”PI: Elizabeth Worthey, PhDHudsonAlpha Institute Home LIZ WORTHEY AND…

Jonas Blomberg, MD, PhD and Anders Rosén, MD, PhD

“Biomarkers of mitochondrial dysfunction and signaling in ME/CFS”PI: Jonas Blomberg, MD, PhD, Anders Rosén, MD,…

Dawei Li, PhD

“Endogenous retroviruses (ERVs) and their expression in chronic fatigue syndrome”PI: Dawei Li, PhDUniversity of Vermont…

Malav Trivedi, PhD

“ME/CFS In a Petri Dish”PI: Assistant Professor Malav Trivedi, PhDNova Southeastern University Home MALAV TRIVEDI…

Hector Bonilla, MD

“Cross-sectional study to assess the prevalence of APOE e4 alleles in patients with ME/CFS and…

2017

The second year of the Ramsays supported five projects investigating the involvement of autoimmunity, infectious triggers, immune cell metabolism, and the gut microbiome in ME/CFS. The 2017 cycle funded a graduate student-level PI to lead a study on the gut virome in a cohort of people with ME/CFS and household controls. It also brought in an expert computational biologist new to the field to study a hypotheses of gut microbiota-immune system interaction using a bioinformatics approach. The group has produced two scientific publications in Frontiers in Immunology from a study initiated by Prof. Jonas Blomberg (Uppsala University, Sweden). More manuscripts from this group are in process.

Jonas Blomberg, MD, PhD and Jonas Bergquist, MD, PhD

“Biomarkers for initiation (infection) and metabolic derangement in ME/CFS”PI: Jonas Blomberg, MD, PhD, Jonas Bergquist,…

Lubov Nathanson, PhD

“Epigenetics in Immune Cells”PI: Lubov Nathanson, PhDNova Southeastern University Home LUBOV NATHANSON “Epigenetics in Immune…

Eran Segal, PhD

“Gut Microbiome & Autoantigens”PI: Eran Segal, PhDWeizmann Institute of Science Home ERAN SEGAL “Gut Microbiome…

Fiona Newberry, PhD Candidate

“Investigating alterations in the intestinal virome in CFS/ME”PI: Fiona NewberryQuadram Institute and the University of…

Carmen Scheibenbogen, MD

“Metabolic Changes in T Cells & Monocytes”PI: Carmen Scheibenbogen, MDCharité—Universitätsmedizin Berlin in Germany  Home CARMEN…

2016

The inaugural group of Ramsay researchers explored hypotheses in diverse areas of science, including: neuroinflammation, autoimmunity, immune cell metabolism, virology, and mitochondrial functioning. To-date, researchers have produced three publications in Frontiers in ImmunologyGenomic Medicine (a Nature publication), and Brain Imaging & Behavior. Dr. Geraldine (Jo) Cambridge and Fane Mensah received extension funding from SMCI for their Ramsay project to investigate altered energy utilization in the B cells of ME/CFS patients in an expanded pool of samples. Notably, pilot data from Dr. Jarred Younger’s Ramsay project showing evidence of neuroinflammation in individuals with ME/CFS was used to obtain a large, multi-year grant from the National Institutes of Health.

Jarred Younger, PhD

“Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance…

Geraldine Cambridge, PhD

“Metabolic Analysis Of B-cell Maturation In ME/CFS”PI: Geraldine (Jo) Cambridge, PhDUniversity College London (UCL) Home…

Bhupesh Prusty, PhD

“HHV-6 Mediated Mitochondrial Modulation and Its Association to ME/CFS”PI: Bhupesh Prusty, PhDUniversity of Wuerzberg Home…

Carmen Scheibenbogen, MD

“Autoimmune Signature in ME/CFS”PI: Carmen Scheibenbogen, MDCharité—Universitätsmedizin Berlin in Germany Home CARMEN SCHEIBENBOGEN “Autoimmune Signature…

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