ME/CFS Research: A Year in Review

An interactive guide to the promising new discoveries of 2018

Written by Rochelle Joslyn (PhD), edited by Allison Ramiller

2018 was a pivotal year for ME/CFS research, yielding over 200 publications specifically addressing various aspects of ME/CFS. Foundational work emerged from prominent biomedical scientists around the globe and powerful new technologies were used to advance our understanding of the disease. From sophisticated neuroimaging to characterization of immune cell dysfunction, the body of work produced this year decidedly situates ME/CFS within the realm of neuroimmune disease.

Studies from the past year encompass a range of domains, illuminating the physiological and biochemical nature of the disease. Reports describe unique elements of the ME/CFS experience, such as post-exertional malaise and social stigma. 2018 has also brought clinical trials of biochemical agents and immunomodulatory techniques. Importantly, substantial re-analyses debunked past trials of therapies rooted in the psychosomatic paradigm. Comprehensive molecular profiling to aid identification of biomarkers and novel therapeutic targets has moved the field closer to the prospect of objective diagnostic measures and novel clinical trials.

Explore highlights from key areas of ME/CFS research: using the interactive graphic below, click or tap on an area of research you want to read more about.

For a text version of this summary, check out Rochelle Joslyn’s blog on medium.

Please note: some studies are interdisciplinary and have relevance beyond the areas of study they are categorized under.