POTS Seen Frequently in CFS

47 patients with postural orthostatic tachycardia syndrome (POTS) referred to the Vanderbilt University Autonomic Dysfunction Center were evaluated for CFS. 64 percent fufilled CDC criteria for CFS (CFS-POTS) and tended to have a longer disease duration than those with POTS alone. Both groups had significant deficit in red cell volume compared to normative data, but were not different from each other. Those who met CFS criteria had highers markers of sympathetic activity than those with POTS alone. There was a trend towards lower aldosterone in the CFS-POTS group. “We speculate that orthostatic intolerance in POTS may be a more important determinant of functional impairment than fatigue…CFS symptoms may arise from a common pathophysiology.” (Clinical Science, Sept. 12, 2011)

Tags: , September 12, 2011