Mitochondrial Exhaustion

In this review, Gerwyn Morris and Michael Maes suggest that an interplay between intracellular molecules such as NF-κB and p53 and mitochondrial dysfunctions are the underlying basis for exhaustion, neurocognitive dysfunction and post-exertional relapse in ME/CFS. They suggest that future research should examine p53 signaling in ME/CFS. (Medical Hypotheses, Aug. 29, 2012)

Tags: , August 29, 2012