Mitochondrial Dysfunction and ME/CFS

Drs. Norman Booth, Sarah Myhill and John McLaren-Howard tested two groups of patients (all met CDC criteria and most met ICC criteria) for defects of energy provision at the cellular level. They found that all patients tested had measureable mitochondrial dysfunction that correleated with illness severity. Patients divided into two main subtypes, A and B, based on how mitochondria compensate for the dysfunction. They acknowledge that while the test may be inclusive and senstive, it may nMitochondria-study-300x268ot be specific to CFS “because there are other neurological illnesses (Parkinson’s and autism) and metabolic syndromes associated with mitochondrial dsyfunction.” (International Journal of Clinical and Experimental Medicine, June 30, 2012)

Tags: , June 30, 2012