Disturbed Metabolic Pathways

Armstrong and colleagues at University of Melbourne published results of a preliminary study analyzing blood samples from 11 CFS patients (2003, Carruthers clinical definition) and 10 non-fatigued controls to identify metabolites as biomarkers for CFS using H NMR spectroscopy. They found significantly decreased levels of glutamine and ornithine in CFS blood samples. They conclude, “Further metabolic analyses … are warranted to improve the knowledge of these metabolite changes and to draw more insight into the underlying biochemical pathways for possible etiologic and clinical significance.” (Clinica Chimica Acta, June 15, 2012)

Tags: , June 15, 2012